What is Naloxone?
is a prescription medicine that is used to reverse an opioid
overdose. Opioids include
and prescription pain medications such as morphine, hydrocodone, and oxycodone.
Naloxone is safe and effective; medical professionals have used it for decades.
Naloxone also goes by the brand names of “Narcan” and “Evzio”.
Naloxone is an antidote to opioid drugs. Opioids can slow or stop a person's breathing, which can lead
death. Naloxone helps the person wake up and
An overdose death may happen hours after taking drugs. If a bystander acts when first noticing
person's breathing has slowed, or when the
person will not wake up it is time
to call 911
rescue breathing (if needed) and administer naloxone.
How does a person administer
can safely and legally spray
naloxone into the nose or inject it into a muscle
The “Good Samaritan” component of the “Opioid Antidote and Overdose Prevention Act” provides
legal protections, both civil and criminal, to the overdose victim and the person who seeks medical
assistance, including the administration of naloxone, for the victim of an opioid overdose.
- Into the nose (intranasal spray):
Naloxone for nasal use is given with the application of an atomizer
that is placed
to a syringe then
placed into each
nostril. Intranasal naloxone has not been approved by the FDA (i.e., it is an "off
delivery method), but it
can be legally prescribed by a physician or approved pharmacist. First
responders often give naloxone intra
- Into the Muscle (intramuscular injection):
also can be
injected into the upper arm muscle (the deltoid) or the outer thigh. In an
emergency, it is safe to inject through clothing.
How long does
Naloxone take to work?
Naloxone acts within 2
-5 minutes. If the person doesn’t wake up after a 5 minute period, bystanders
a second dose. Rescue breathing should be done while you wait for the naloxone to
Naloxone typically wears off within 30
-90 minutes following administration.
What are the next steps following administration of Naloxone?
-1-1 and stay with the individual. If you are in a position to help the overdose victim get into
treatment for opioid addiction, learn about the available resources and
encourage his/her treatment